Immunohistochemistry Catalog

CD117 (c-kit)

Clone: PC
Cat#: 10086
This antibody reacts with a 145 kDa molecular weight protein, designated as CD117/c-kit. C-kits are transmembrane receptor tyrosine kinases expressed in many tissues and cells and are involved in the development of severa l lineages of stem cells such as germ cells, neuronal crest derived melanocytes and hematopoietic precursor cells. Useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, and tumors of smooth muscle origin.
Fixed-embedded human naevus
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