Staff

Ferenc Boldizsar MD, PhD

boldizsar-ferencjav
Associate Professor
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+36-72-536-288 / 36525
  • 1997-2000. Reasearch student
  • 2000.- PhD student
  • 2003.- Assistant Professor
  • 2005.- Lecturer
  • 2012.- Associate Professor at the Department of Immunology and Biotechnology, Clinical Center, University of Pecs
  • 2004. PhD degree (title: The role of glucocorticoid hormon in thymocyte selection: modell studies in BALB/c and T-cell receptor transgenic (AND) mice Tutor: Tímea Berki MD, PhD, Associate Professor
  • 2012. Habilitation
  • 1990-1994. Pécsi Apáczai Csere János Gimnázium, Angol-Magyar kéttannyelvű osztály
  • 1994-2000. Pécsi Orvostudományi Egyetem, Általános Orvos Kar
  • Rush University Medical Center
    • Section of Molecular Medicine, Departments of Orthopedic Surgery, Biochemistry, and Medicine (Section of Rheumatology), Chicago, IL, USA
    • 2006-2008, Research Fellow (Supervisor: Prof. Dr. Tibor Glant)
  • 1997 – 2000: Studying the effect of in vitro hyperglycaemia on the calcium signaling of a human T cell line. (Supervisor: Tímea Berki MD, PhD)
  • 2000-2006: Studying thymic selection processes in wild type or T cell receptor transgenicmouse models. The regulatory role of glucocorticoid hormon in T cell develpoment and apoptosis. Potential mechanisms of non-genomic glucocorticoid actions in T cells. Interaction between ZAP-70 (T-cell receptor signaling molecule) and glucocorticoid receptor signaling pathways in T cells. (Supervisor: Tímea Berki MD, PhD)
  • 2006-2008: The role of T cells in the development of systemic autoimmunity in a rheumatoid arthritis mouse model. Investigatio of susceptibility factorsfor arthritis in mouse model: role of cytokines, local factors and genetic background. Role of activation induced cell death in the pathogenesis of rheumatoid arthritis. (Supervisor: Prof. Tibor Glant MD, PhD) 
  • 2009-: Characterization of the mitochondrial translocation of the glucocorticoid receptor in developing T cells.Cross-talk between the T cell receptor and glucocorticoid receptor signaling pathways in T cell model.
  • Cell- and tissue culturing(cell lines, short term mouse spleen cultures).
  • Flow cytometry: cell surface- and intracellular labeling, intracellular Ca level measurement, fluorescent cell sorting. Several years experience with FACS Calibur, FACS Vantage SE and FACS Canto II cytometers.
  • Molecular biology: PCR, RT-PCR, real-time PCR, cloning, restriction analysis, lentiviral transfection system, transient and permanent expression of normal or modified proteins in pro- and eukaryotic cells.
  1. Pécsi Tudományegyetem, Általános Orvostudományi Kar Tudományos Bizottsága, "Alapítvány az Orvosképzés Támogatására"; „A ZAP-70 fehérje tirozin maradékok mutációinak vizsgálata Jurkat sejteken site-directed mutagenesis felhasználásával”; 2004.
  2. Pro Renovanda Cultura Hungariae „Tudomány az Oktatásban“ szakalapítvány; az Immunológiai és Biotechnológiai Intézet internetes oktatási anyagának fejlesztésére; 2005.
  3. Magyary Zoltán Posztdoktori Ösztöndíj (Magyary Zoltán Közalapítvény, Norway Grants); „A ZAP-70 kináz nem-genomikus glukokortikoid hatásban betöltött szerepének vizsgálata”; 2010-2011.
  4. OTKA-K101493. „A ZAP-70 kináz szerepének vizsgálata egy rheumatoid arthritis modell patogenezisében”; Vezetó kutató; 2012-2016.
  5. OTKA-K105962. “A glucocoticoid hormon (GC) jelátviteli útvonal szerepének vizsgálata regulatórikus T sejtek differenciálódásában és működésében.”; Senior társkutató; 2013-2017.
  6. Bolyai János Kutatási Ösztöndíj (Magyar Tudományos Akadémia); 2012-2015.
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