Napsin A is a 35.0 kDa molecular weight aspartic proteinase which is expressed in the lung and involved in processing surfactant protein B (SP-B). It is also expressed in the kidney. This antibody may be a useful tool as a tumor marker for prima ry lung adenocarcinoma. Napsin expression correlates with the differentiation grade of lung adenocarcinoma.
Fixed-embedded human lung adenocarcinoma