Cat#: DB 148
Desmin is an intermediate filament protein of both smooth and striated muscles. E18-reacts with striated (skeletal V and cardiac) as well as smooth muscle cells. In skeletal and cardiac muscles, the staining is confined to the Z-bands giving a characteristic striated appearance. Useful in indication of tumors of myogenic origin. It reacts with leimyosarcomas, as well as, rhadbomyosarcomas (striated muscle).
Fixed-embedded human uterus leiomyoma