Cat#: DB 045
CD163 is present on all circulating monocytes and most tissue macrophages except those found in the mantle zone and germinal
centres of lymphoid follicles, interdigitating reticulum cells and Langerhans cells. In addition, multi-nucleated cells within inflammatory lesions are reported not to express CD163 protein. It has been proposed
that a specific release mechanism of soluble CD163 antigen by human monocytes may play an important role in inflammatory processes.
Fixed-embedded human placenta