Immunohistochemistry Catalog

p16

Clone: R19-D
Cat#: DB 152
P16 plays an important role in cell cycle regulation by decelerating cells progression from G1 phase to S phase, and therefore acts as a tumor suppressor. Hypermethylation, mutation, or deletion of p16 leads to downregulation of the gene and can lead to cancer through the dysregulation of cell cycle progression. Double staining with Ki-67 can provide insight into cell cycle status.
DB 152
Fixed-embedded human cervix cancer
Elhelyezve itt: Rabbit Clonal Anti-