ER (Estrogen receptor)
Cat#: DB 053
This antibody recognizes a protein of 67 kDa, which is identified as estrogen receptor (ER) and stains the nucleus of epithelial cells in breast carcinomas. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast cancers indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Fixed-embedded human breast cancer